Cheap Flights from Roanoke to St Louis

Compare Roanoke to St Louis flight deals

Find the cheapest month or even day of the year to fly to St Louis

Book the best St Louis fare with no extra fees

Flight deals from Roanoke Airport to St Louis Airport

Looking for a cheap last-minute deal or the best return flight from Roanoke to St Louis? Find the lowest prices on one-way and return tickets right here.

Find the cheapest month to fly from Roanoke to St Louis

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Roanoke to St Louis flights are currently cheapest in March.

Roanoke to St Louis: Alternative routes

Compare routes from Roanoke to St Louis below. You may find an airport to fly into that's cheaper, faster, or easier than St Louis.

Roanoke to St Louis: Flight information

The things to know before you go.
Cheapest flight foundر.ق.‏ 1,361
Cheapest month to flyMarch

Finding cheap flights from Roanoke to St Louis: Frequently asked questions

The best price we found for a return flight from Roanoke to St Louis is ر.ق.‏ 1,114. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
Currently, there are no airlines that fly direct from Roanoke to St Louis. But we found flights with one or more stops from ر.ق.‏ 1,114.
As of March 2026, there are no flights flying from Roanoke to St Louis.
The cheapest month to fly from Roanoke to St Louis is usually March.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Roanoke Airport to St Louis Airport on Friday, 13 March 2026.
No airlines currently offer direct flights between Roanoke Airport and St Louis Airport. Most routes have one or more stops.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to St Louis but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to St Louis is around 40 days in advance, so don’t leave your flight to the last minute.
Currently, United offers the cheapest flight tickets to St Louis.

Flying from Roanoke-Blacksburg Regional Airport (ROA) to Lambert-St. Louis International Airport (STL): what you need to know

  • St Louis's timezone is UTC-5, making St Louis one hour behind Roanoke.

  • Arriving two hours before an international flight and one hour ahead of a domestic departure are golden rules for stress-free travel. Be at the airport on time to board your ROA to STL flight.

  • During popular months like August, you'll want to get to the airport well in advance. Arrive two hours before domestic departures and four hours ahead for international flights when you travel during peak periods in general.

  • If you want to add a stop to your trip, simply uncheck 'Direct flights only' when searching for your ticket from Roanoke-Blacksburg Regional Airport to Lambert-St. Louis International Airport. These are the top stopovers between ROA and STL:

    • Charlotte Douglas International Airport

    • Hartsfield-Jackson Atlanta International Airport

    • O'Hare International Airport

How to find the cheapest flights from Roanoke-Blacksburg Regional Airport (ROA) to Lambert-St. Louis International Airport (STL)

  • Right now, ر.ق.‏ 1,361 is the lowest price we've seen for a one-way Roanoke-Blacksburg Regional Airport to Lambert-St. Louis International Airport flight. The best price for a return ticket is ر.ق.‏ 1,114. Remember that fares can change due to availability at the time of booking.

  • It's a good idea to book in advance if you're hoping to get cheap tickets from ROA to STL. That's because flight prices are based on demand, which tends to increase closer to departure.

  • If you can be flexible with your travel dates, use the 'Whole month' search tool. It'll show you the lowest price across the month when looking for a flight from Roanoke-Blacksburg Regional Airport to Lambert-St. Louis International Airport.

  • Getting your hands on cheap flights from ROA to STL is easy with Price Alerts. All you need to do is set up one of these automatic alerts and we'll let you know as soon as there's a better deal.

  • Choose your preferred departure and arrival times, number of stops and airlines with the filters. Or sort your results by 'Cheapest' to get the best deals on flights from Roanoke-Blacksburg Regional Airport to Lambert-St. Louis International Airport.

Handy information about Roanoke-Blacksburg Regional Airport (ROA)

  • You'll find ROA at 5202 Aviation Drive, N.W..

  • When it comes to Roanoke-Blacksburg Regional Airport's on-time performance, 68.76% of flights arrive within the expected timeframe.

  • To reach Roanoke-Blacksburg Regional Airport from central Roanoke, it takes around 10 minutes if you're planning to drive. Of course, this depends on traffic. It's approximately 8 kilometres from the airport to the city centre.

  • Planning to take public transport? Expect a trip time of around 35 minutes.

  • Have an early flight from Roanoke-Blacksburg Regional Airport to Lambert-St. Louis International Airport? Avoid rushing to the airport (and enjoy a little extra shut-eye) by choosing one of these stays near ROA:

Arriving at Lambert-St. Louis International Airport (STL)

Getting from Lambert-St. Louis International Airport (STL) to central St Louis

  • STL is located at 10701 Lambert International Blvd..

  • From Lambert-St. Louis International Airport, St Louis is approximately 26 kilometres away. It takes around 20 minutes to get to the centre driving.

  • If you're travelling by public transport, expect a journey of around 35 minutes.

When to fly to Lambert-St. Louis International Airport (STL)

  • July is the busiest month for flights from Roanoke-Blacksburg Regional Airport to Lambert-St. Louis International Airport. For smaller crowds, head to St Louis in April.

  • Lock in your flight from Roanoke-Blacksburg Regional Airport to Lambert-St. Louis International Airport for July if you'd like to explore St Louis during its warmest month. Expect temperatures of between 17ºC and 33ºC.

  • If you want to travel in cooler conditions, look for a cheap ticket from ROA to STL in January. Temperatures average between -8ºC and 7ºC then.

Explore more of United States

  • Chicago is just one of the many places in United States waiting to be explored after you've experienced St Louis. Around 418 kilometres away to the north-east, well-known attractions include Millennium Park, Art Institute of Chicago and LandShark Beer Garden at Navy Pier.

  • If you're eager to discover another well-known destination in United States, consider Indianapolis, roughly 370 kilometres east of St Louis. The Children's Museum of Indianapolis, Indianapolis Museum of Art and Indianapolis Zoo are highlights.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.