Cheap Flights from Cuzco to Panama City

Compare Cuzco to Panama City flight deals

Find the cheapest month or even day of the year to fly to Panama City

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Flight deals from Cuzco to Panama City

Looking for a cheap last-minute deal or the best return flight from Cuzco to Panama City? Find the lowest prices on one-way and return tickets right here.

Find the cheapest month to fly from Cuzco to Panama City

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Cuzco to Panama City flights are currently cheapest in May.

Alternative Cuzco to Panama City routes

Looking for the cheapest, fastest or easiest route from Cuzco to Panama City? You could fly into the following airports instead.

Cuzco to Panama City: Flight information

The things to know before you go.
Cheapest flight foundر.ق.‏ 715
Cheapest month to flyMay

Finding cheap flights from Cuzco to Panama City: Frequently asked questions

There are 3 airports in Panama City: Panama City Paitilla, Balboa and Panama City Tocumen International.
The best price we found for a return flight from Cuzco to Panama City is ر.ق.‏ 1,625. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
Currently, there are no airlines that fly direct from Cuzco to Panama City. But we found flights with one or more stops from ر.ق.‏ 1,625.
As of September 2025, there are no flights flying from Cuzco to Panama City.
The cheapest month to fly from Cuzco to Panama City is usually December.
If you're flying from Cuzco Airport, the cheapest airport near Panama City is Panama City Tocumen International – which is 17.9 km away from the centre of Panama City. We've found flights into this airport from ر.ق.‏ 1,625.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Cuzco Airport to Panama City on Thursday, 11 December 2025.
No airlines currently offer direct flights between Cuzco Airport and Panama City. Most routes have one or more stops.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Panama City but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Panama City is around 40 days in advance, so don’t leave your flight to the last minute.
In September, the average temperature is usually around 27°C. May is typically the warmest month in Panama City, when it usually averages around 29°C. You can expect the least rain in February. The coldest month is October, with temperatures averaging 25°C. The rainiest month is June.
Currently, Avianca offers the cheapest flight tickets to Panama City.

Flying from Alejandro Velasco Astete International Airport (CUZ) to Panama City: what you need to know

  • Panama City's timezone is UTC-5, which is the same as Cuzco (the location of Alejandro Velasco Astete International Airport).

  • Leave plenty of time to make your CUZ to Panama City flight. Generally, it's best to arrive two hours before international departures and an hour ahead for domestic flights.

  • Taking off during a peak period like public or school holidays? Expect longer lines at check-in and security. To be on the safe side, arrive up to four hours before international flights and two hours before domestic departures.

  • Stopovers offer a great opportunity to explore a new place or just take a break during your journey. When booking your flight ticket from CUZ to Panama City, uncheck 'Direct flights only' to browse all potential stops. El Dorado International Airport (BOG) is a top stop on this route.

  • Travelling from central Cuzco to CUZ takes around 40 minutes by public transport. If you ride-share, drive or get a cab, you'll cover the 3 kilometres in 10 minutes or so, depending on traffic.

  • Catching an early flight from Alejandro Velasco Astete International Airport to Panama City? Avoid the stress of rushing to the airport (and get some extra shut-eye) by choosing one of these hotels near CUZ:

  • When it comes to Alejandro Velasco Astete International Airport's on-time performance, data shows 68.13% of flights meet their scheduled arrival time.

How to find the cheapest flights from Alejandro Velasco Astete International Airport (CUZ) to Panama City

  • The best price we've found for a one-way Alejandro Velasco Astete International Airport to Panama City flight is ر.ق.‏ 715. The cheapest price for a return flight is ر.ق.‏ 1,625. Remember fares can change due to demand at the time of booking.

  • Booking in advance is often the key to securing a cheap flight from CUZ to Panama City. Airlines adjust prices based on demand, so the closer you get to departure, the more you'll likely pay.

  • Scoring cheap tickets from Alejandro Velasco Astete International Airport to Panama City is easier if you can be flexible with your travel dates. Use the 'Whole month' tool to get the best prices across each month and bag a sweet deal.

  • Save time searching for cheap flights from CUZ to Panama City by setting up a Price Alert. You'll get an email or push notification on the app when a lower fare pops up.

  • Select your ideal departure and arrival times, number of stops and airlines with our filters. Then, sort the results for your flight from Alejandro Velasco Astete International Airport to Panama City by 'Fastest,' 'Cheapest' or 'Best.'

Airports in Panama City

Tocumen International Airport (PTY)

  • Tocumen International Airport (PTY) is around 21 kilometres from the centre of Panama City. If you're catching a cab or a ride-share, the drive takes roughly 20 minutes.

  • Travelling on public transport takes about 1 hour 5 minutes.

  • The last thing you want is a long journey to your hotel if you're landing late on a flight from Alejandro Velasco Astete International Airport to Panama City. Reserve one of these accommodation options near PTY instead:

  • Grab a Tocumen International Airport rental car and discover Panama City and beyond with your own wheels. Avis, Dollar and MEX are leading providers you can book with here.

  • For the best deal, book your ride from Tocumen International Airport about three weeks ahead of your flight from CUZ to Panama City.

Marcos A. Gelabert International Airport (PAC)

  • Marcos A. Gelabert International Airport (PAC) is around 2 kilometres from central Panama City. Once you've hopped off your flight from Alejandro Velasco Astete International Airport to Panama City, it'll take you around 5 minutes to reach the heart of the city in a cab or ride-share.

  • If you're travelling on public transport, it'll take around 25 minutes.

  • Hang the 'Do not disturb' sign on your door and rest at a hotel close to PAC. Here are a few options where you can put your feet up after your CUZ to Panama City flight:

  • Forget about public transport timetables or long cab lines. Pick up a Marcos A. Gelabert International Airport rental car and let the journey unfold your way. Compare availability and rates from Thrifty, Avis and Alamo.

  • Lock in the best price by reserving your ride from PAC three weeks ahead of time. You can also expect to have a wider range of vehicles.

Panama Pacifico Airport (BLB)

  • Hop off your flight from Alejandro Velasco Astete International Airport to Panama City and go straight to your hotel or start sightseeing right away. Central Panama City is around 16 kilometres from Panama Pacifico Airport (BLB) and usually takes 20 minutes to reach driving.

  • Enjoy an unhurried start to your trip by staying at a hotel near BLB after your CUZ to Panama City flight. Unwind after a day of travel or simply give yourself time to get your bearings in a new destination at:

  • Start your journey without worrying about how to get to your destination with a Panama Pacifico Airport rental car. Find your perfect set of wheels with trusted suppliers here like Sixt, Dollar and Thrifty.

  • Enjoy a payoff when you plan ahead. Book your ride from BLB one week before your flight from Alejandro Velasco Astete International Airport to Panama City for the most affordable rates.

Best time to go to Panama City

  • Carefully consider your travel dates before securing your flight from Alejandro Velasco Astete International Airport to Panama City. The city buzzes during peak season, but hotel rates are usually higher and attractions can be crowded. Plan your trip to Panama City in low season for a quieter vibe.

  • The warmest month in Panama City is March, with temperatures ranging between 21ºC and 32ºC. Lock in your Alejandro Velasco Astete International Airport to Panama City flight ticket then if that's your idea of comfortable weather.

  • If you like travelling in cooler conditions, look for a cheap ticket from CUZ to Panama City in February when temperatures average between 22ºC and 31ºC.

More about Panama City

  • Once you've booked your flight from Alejandro Velasco Astete International Airport to Panama City, choose a hotel that puts you right where the action is. Make one of these accommodation options your base for exploring Panama City:

  • Casco Viejo and Panama Canal Museum are a couple of top-rated attractions to put on your Panama City travel itinerary. Keep the momentum going by heading to Cinta Costera.

Explore more of Panama

  • Panama City has its own special appeal, but there are so many other corners of Panama you should also see. About 322 kilometres west of Panama City, a visit to David will keep your itinerary packed. Check out popular attractions like Parque Cervantes, Altos del Rio Park and Coquito Hills Park.

  • Around 193 kilometres south-west of Panama City, Santiago de Veraguas is another favourite stop in Panama. Experience major highlights starting with Santiago the Apostle Cathedral, Santiago de Veraguas, The Church of Jesus Christ of Latter Day Saints and La Placita San Juan De Dios.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.